At Which to Spay and Neuter: An Evidence-Based Analysis

By Margaret Root-Kustritz, DVM, PhD   University of Minnesota

This interesting review paper outlines some breed-based health issues as well as the impact of sterilization on dogs.  It is very interesting and thorough, with a good list of references for further reading.

The paper is available at the AKC Canine Health Foundation page:

http://www.akcchf.org/pdfs/whitepapers/3-23-08DiscoveriesArticle.pdf